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 A Why has it taken so long for ACP to enter the marketplace? If calcium phosphate is such hot stuff, why has information technology taken and then long to find its fashion into dental products? It's not as uncomplicated as dabbing minerals straight onto teeth, Dr. Tung explains, because in solid class they won't bind to the teeth. Instead, he has worked with a chemical compound called amorphous calcium phosphate (ACP) which, when combined with water, crystallizes onto the teeth in the grade of new enamel. The Australian squad, led by Eric C. Reynolds, AO, caput of the school of dental scientific discipline at the University of Melbourne, Australia, took a dissimilar approach to ACP. They noticed that milk products seemed to have benign effects on molar enamel and realized that casein phosphopeptides (CPP) could stabilize the molecules until they are practical to teeth, and help demark them to plaque, bacteria, soft tissue, and dentin where they are slowly released to form enamel. The Australians take licensed their formula for CPP-ACP to GC America, which sells it equally MI Paste in the U.s. and Canada and Molar Mousse elsewhere. Does MI Paste have the ADA Seal of Acceptance? What is the ADA Seal of Acceptance Plan? The ADA decided non to utilize the seal program for prescription products subsequently January 1, 2008. The ADA instituted the Professional Product Review (PPR) in place of the seal program for this category. The PPR is provided costless to ADA members (and past subscription to others) four times a twelvemonth and includes comparative evaluations of a number of products in a category with usually three product categories per issue. The ADA concurrently made the decision to concentrate on the PPR and to eliminate the Seal Program for professional and prescription products. Consequently, professional person and prescription products are no longer eligible for the ADA Seal of Acceptance. Still, the Seal Program for consumer products remains in place to keep to aid consumers brand informed consumer product decisions. When consumers see the ADA Seal on a product, they tin can be bodacious that information technology has undergone a rigorous objective, scientific review of its prophylactic and effectiveness. The Seal on product labeling ways that the product says what it does and does what it says. Although it is strictly voluntary, more than 100 companies participate in the Seal program. Participating companies commit significant resources to test and market place products in the Seal plan. More than 400 dental products that are sold to consumers carry the Seal of Acceptance. These include toothpaste, dental floss, manual and electric toothbrushes, rima oris rinse and chewing gum. ADA Seal: List of Credence for Consumer Products How to apply MI Paste Plus? Just like MI Paste, MI Paste Plus is applied topically to at-chance surfaces. This tin be washed past first cleaning the teeth and then smearing a small amount of MI Paste Plus across the tooth surfaces with a clean finger or cotton-tipped applicator. When practical immediately earlier bed, the textile is and so left in place, to deliquesce slowly overnight. Information technology is non rinsed out. MI Paste Plus can as well be practical topically to the teeth using a custom-made tray such as a pull-down tray fabricated for applying a whitening gel. - Employ using a clean finger or custom tray
- Leave undisturbed for a minimum of 3 minutes
- Spread around the mouth and teeth with the tongue and concur for one to 2 minutes
- Expectorate, do non rinse and avoid food or drink for 30 minutes
- Nightly awarding is the standard recommendation
- For high risk patients, apply both morning and night
Does MI Paste/MI Paste Plus contain corn and any derivatives of corn? Corn is not an ingredient of MI Paste/MI Paste Plus. Please consult your doc or dentist prior to using MI Paste or MI Paste Plus with any concerns. -
Will MI Paste alleviate sensitivity from bruxism? The occlusion or bite is causing the sensitivity and until that is corrected MI Paste will not eliminate the sensitivity. The sensitivity is due to the occlusion and the clenching and unfortunately MI Paste would probably not convalesce the sensitivity. Tin you brush on MI Paste/MI Paste Plus? MI Paste/MI Paste Plus can be applied with cotton wool swab, glove, clean finger or with a custom tray. If using a toothbrush, utilise equally an applicator. MI Paste/MI Paste Plus is not a conventional toothpaste. How soon afterward I brush exercise I apply MI Paste? Later brushing with an over the counter toothpaste (1,000 ppm fluoride) immediately apply a pea-size amount of MI Paste to the tooth surfaces using either a clean finger or a cotton swab. Does MI Paste/MI Paste Plus incorporate Bis-Phenol A (BPA)? Because the contempo inquiries we would similar to confirm that GC dental products sold in the United states of america, Canada or Latin America do not contain Bis-Phenol A (BPA) equally an ingredient. Also GCA does non import any products into the United states of america of America, Canada or Latin America containing Bis-GMA. Breast-feeding, Pregnancy and MI Paste MI Paste is rubber during a pregnancy and MI Paste is condom to use while you are breast-feeding. Regular use of MI Paste during pregnancy helps to maintain elevated levels of calcium and phosphate in the saliva. MI Paste is a rubber product to utilize for babies teeth and is well tolerated by children and tastes delicious. MI Paste is particularly useful for children under two years of age, raising the levels of minerals. RECALDENT™ (CPP-ACP) is derived from the milk poly peptide casein chosen casein phosphopeptide. Exercise non apply on patients with a milk protein casein allergy. Regular use of MI Paste during pregnancy will help soothe sensitive teeth. Breast-feeding and fluoride pertaining to MI Paste Plus Breast milk is widely acknowledged every bit the most consummate course of nutrition for infants. The American Academy of Pediatrics recommends human milk for all infants (except for the few for whom breast-feeding is adamant to exist harmful). Babies who are breast fed do not appear to exceed the optimal amount of fluoride. Breast milk is very low in fluoride. Nursing mothers or significant women who drink fluoridated h2o do not pass on pregnant amounts of fluoride to their child. Based on the higher up argument, it appears significant amounts of fluoride does non pass through breast milk. Delight annotation, the levels of fluoride in MI Paste Plus is 900 ppm, that is similar to the amount of fluoride in over the counter toothpaste. Information technology appears significant amounts of fluoride is not contained in breast milk and thus fluoride is not passing on to the child during breast-feeding. Equally always, delight discuss with your personal physician if you have further questions. -
Is MI Paste/MI Paste Plus safe to utilise for my true cat or dog? MI Paste and MI Paste Plus have never been tested on cats or dogs. We recommend you bank check with your veterinarian. All the ingredients are listed on the box/tube for your veterinarian to make a professional person conclusion. Milk is listed as an ingredient that should not exist given to pets according to the American Society for the Prevention of Cruelty to Animals (ASPCA). Take your box and tube of MI Paste/MI Paste Plus to your veterinarian and testify him/her the ingredients that are listed; your professional veterinary knows what is acceptable for your favorite pet's wellness. Please note: MI Paste does not contain fluoride; MI Paste Plus does comprise fluoride. Is MI Paste Plus condom to employ on children? Because MI Paste Plus contains a level of fluoride similar to that of developed forcefulness toothpastes, at that place are issues when the cloth is ingested either accidentally or deliberately in children because of their depression nascence weight. Ingestion of a pea-size amount (0.5 mL) of MI Paste Plus will contribute 0.45 mg of fluoride ion to the daily fluoride intake. In immature children (up to six years of age), use of MI Paste Plus is contra indicated because information technology may increase the hazard of dental fluorosis. Children aged 6 years and above tin use both standard (adult strength) toothpaste (1000 ppm) and MI Paste Plus without an increased risk of dental fluorosis. - MI Paste Plus contains 0.ii% (900 ppm) fluoride; it is not recommend for children under 6
- Information technology is not recommended for overnight application in children under 12
- Do not use on patients with a milk protein allergy (caesin IgE) and/or sensitivity to benzoate preservatives
Why is calcium so important? It is critical to sustain the bio-available calcium ion level inside the saliva, to strengthen the molar structure before attempting to restore information technology. Using fluoride products alone is insufficient to cause strengthening to occur because the critical pH of enamel relates strongly to the calcium concentration in the saliva and the plaque fluid. To maintain as high a level of calcium in the plaque fluid as possible, apply MI Paste Plus each morning time and over again each night, immediately earlier retiring. This contains and releases calcium, phosphate and fluoride ions in the correct ration (5:iii:one). If a patient is a high caries risk, a dwelling house plan may continue to include high fluoride concentration toothpaste or gel on an intermittent basis to suppress plaque levels and suppress plaque fermentation. Apply a detergent-free normal strength toothpaste morning time and night, only a high forcefulness (5000 ppm) fluoride toothpaste or gel (9000 ppm) in the eye of the day, in gild to exert antibacterial furnishings, and to forbid potential problems with sequestering calcium ions. Why not to employ antimicrobial rinse such as chlorhexidine gluconate within ii hours of using fluoride toothpaste containing sodium lauryl sulfate? It is suggested non to employ antimicrobial rinses, such equally chlorhexidine gluconate (CHA) or cetylpyridinium chloride (CPC) within 2 hours of fluoride toothpaste containing sodium lauryl sulfate because the sodium laurel sulphate saponification component in dentifrice can reduce chlorhexidine activity. What is Cetylpyridinium Chloride (CPC)? CPC is a cationic quaternary ammonium compound in some types of mouthwashes, toothpastes, lozenges, throat sprays, anti-snore throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis. It has likewise been used as an ingredient in certain pesticides. This ingredient has too been shown to cause brownish stains between the teeth. CPC has a positive cationic (Sodium Laurel Sulfate is negative) resulting in negating the desired effect. Crest Pro-Wellness Rinse contains CPC, how does it work? Crest Pro-health Rinse contains a clinically proven bactericidal amanuensis, CPC that'south attracted to leaner in the mouth. CPC interacts with the bacterial membrane and weakens information technology. The cellular force per unit area disrupts the cell membrane and kills the bacteria. What is the protocol with Chlorhexidine Gluconate and MI Paste? It is suggested to wait 2 - iii hours after rinsing with antimicrobial rinses, such equally chlohexidine gluconate (CHX) or cetylpyridinium chloride (CPC) before applying MI Paste. Chlorhexidine gluconate adheres to the molar surface just as MI Paste, so it is all-time to wait 2-3 hours before applying MI Paste later rinsing with CHX. What goes showtime? How long should a patient look between applying Chlorhexidine Gluconate (CHX) and MI Paste and will they affect each others efficiency? It is best to wait 2-iii hours afterward rinsing and applying MI Paste. Every bit to which goes first the guild is not the important cistron just that there is sufficient time betwixt applications. How immature tin a child be to apply MI Paste? MI Paste is a condom product to use for babies' teeth and is well tolerated by children and tastes delicious. MI Paste is especially useful for children nether 2 years of historic period, where toxicological problems mean normal or high strength fluoride products are contraindicated. MI Paste is a safety product to use for babies' teeth and is well tolerated by children and tastes succulent. RECALDENT™ (CPP-ACP) is derived from the milk protein casein chosen casein phosphopeptide. Exercise non utilize on patients with the milk protein casein allergy. Newly erupted teeth have yet to complete their enamel maturation and until this occurs they are more vulnerable to an acid assail. Boosting levels of calcium and phosphate in the saliva facilitates the normal post-eruption maturation process and helps decrease dentin hypersensitivity. RECALDENT™ (CPP-ACP) is derived from cow's milk and is ideal for providing relief for deciduous teeth at a time when oral care is difficult. MI Paste is applied to the teeth twice daily with a clean finger to provide a surface flick that will raise levels of essential minerals (calcium and phosphate), too as inhibit the growth of caries causing bacteria. At what age can children utilize MI Paste Plus? MI Paste Plus, which contains 900 ppm fluoride ions (0.2% sodium fluoride), is not recommended for children under six years of age. Is there an increase in supra-gingival calculus associated with the use of MI Paste? Casein Phosphopeptides (CPP) inhibits the transformation of baggy calcium phosphate into crystalline phases (Holt and van Kemenade, 1989) such that they should not directly promote calculus formation but instead provide a plaque reservoir of soluble calcium phosphate ions capable of diffusing into subsurface enamel and promoting a strong and healthy oral environment. How much calcium is in MI Paste? The amount of calcium contained in MI Paste is thirteen mg/g. Canker sores and MI Paste Canker sores are shallow, painful sores in the mouth. They are usually red or may sometimes have a white coating over them. You might get them on the within of your lips, the insides of your cheeks, the base of your gums or under your tongue. Anyone tin go canker sores, merely women and people in their teens and 20s get them more oftentimes. Canker sores may run in families, but they aren't contagious. Doctors don't know what causes canker sores, but they may exist triggered past stress, poor diet, food allergies and menstrual periods. The acid from strawberries and tomatoes may also exist a contributing gene. MI Paste/MI Paste Plus does non have whatever history of causing canker sores. Hydroxybenzoate, often chosen paraben and is widely used as a preservative in the cosmetic and pharmaceutical industries, such as shampoos, lotions, toothpaste, etc. Information technology is also used equally a food additive. Parabens are considered to be prophylactic, but tin crusade skin irritation or dermatitis on some individuals with paraben allergies. With that in mind, that is why the caution statement is posted on the box: "RECALDENT™ is derived from milk casein. Do not use on patients with a milk protein and/or hydroxybenzoate allergy." It is suggested that the patient temporarily terminate using MI Paste/MI Paste Plus until the canker sores take healed. Once the canker sores have healed, the patient may want to resume applying MI Paste Plus. As mentioned to a higher place, information technology could be acquired from stress, nutrition or food allergies, not relating to MI Paste Plus. It is ever wise to check with a physician or dentist. Does MI Paste/MI Paste Plus contain corn and any derivatives of corn? Corn is non an ingredient of MI Paste/MI Paste Plus. Delight consult your physician or dentist prior to using MI Paste or MI Paste Plus with any concerns. -
Is MI Paste/MI Paste Plus safe to use for my cat or dog? MI Paste and MI Paste Plus accept never been tested on cats or dogs. We recommend you cheque with your veterinarian. All the ingredients are listed on the box/tube for your veterinarian to make a professional conclusion. Milk is listed as an ingredient that should not be given to pets according to the American Society for the Prevention of Cruelty to Animals (ASPCA). Take your box and tube of MI Paste/MI Paste Plus to your veterinarian and show him/her the ingredients that are listed; your professional person veterinarian knows what is acceptable for your favorite pet'due south wellness. Delight note: MI Paste does not contain fluoride; MI Paste Plus does contain fluoride. I am not a dentist, my dentist prescribed MI Paste simply I can't find a chemist's shop that can fill up the prescription, what practise I do? As a company we do not sell directly; MI Paste is only sold to the dental profession through their dental dealer. If your dentist prescribed MI Paste more than likely he will accept it in his office. Your dentist can e'er purchase MI Paste through his local dental dealer. Can a patient on kidney dialysis utilize MI Paste? Dialysis patients must seek approval from their physician before using MI Paste/MI Paste Plus, although the amount of ingestion of phosphate by using MI Paste would exist very pocket-size. Consultation between physician and dental professional may lead to a modification of the therapeutic application. The corporeality of phosphate contained in a MI Paste 40g tube is more than 0.two%. We say "more than" because 0.ii% is phosphoric acid by itself and CPP-ACP too contains phosphate. The recommended therapeutic dose is 1 gm. per application. Though this product can be ingested subsequently therapeutic application it is not how the product is used to evangelize a therapeutic dose. Note, We do not show a warning most phosphate for dialysis patients in the instructions. Instead, we show all the ingredients on the tubes and boxes. -
Can MI Paste be used on patients with dental erosion? Gastric Reflux, commonly referred to equally indigestion or upset tummy, causes tummy acids to travel up the esophagus and into the mouth. If these chemicals reach the teeth information technology can erode the enamel and dentin resulting in sensitivity, disuse, yellowing and thinning of the teeth. This process likewise makes the mouth more susceptible to infection and the oral tissues more susceptible to ulcers or sores. Gastric Reflux occurs in diverse cases and may be linked to nutrient and beverage consumption, chronic conditions, medications and treatments, pregnancy or any number of other sources. Physicians can help treat and prevent the occurrence of gastric reflux merely episodes will result in damage to the oral surround. MI Paste and MI Paste Plus release calcium and phosphate (and as well sodium fluoride in MI Paste Plus) when and where they are needed near. MI Paste and MI Paste Plus save tooth sensitivity. -
How does MI Paste Plus compare to Fluoride rinse or varnish? Fluoride rinses contain betwixt 200 and 900 ppm fluoride, while varnishes contain between 22,600 and 25,000 ppm fluoride. These can be effective preventive agents in patients with enhanced take a chance, but normal salivary office. MI Paste Plus has 900 ppm of fluoride. MI Varnish™ has 22,600 ppm of fluoride, and is for moderate to high caries risk. Too MI Varnish™ could be benign in cases where compliance is an issue. Can you utilize MI Paste/MI Paste Plus with RECALDENT™ (CPP-ACP) after brushing or rinsing with a fluoride toothpaste or oral rinse? Information technology is okay to brush or rinse with fluoride products prior to applying MI Paste/MI Paste Plus with RECALDENT™ (CPP-ACP). It is acceptable to use MI Paste/MI Paste Plus with RECALDENT™ (CPP-ACP) after brushing with an "over the counter toothpaste" (900/1000 ppm fluoride) as well every bit later brushing with a high fluoride prescription toothpaste (5000 ppm fluoride). The same goes for rinsing with a loftier fluoride oral rinse before applying MI Paste/MI Paste Plus topical creme with RECALDENT™ (CPP-ACP). When applying MI Paste/MI Paste Plus information technology is all-time not to disturb the topical creme, not having anything to swallow or drink (including oral rinses) for thirty minutes to maximize the uptake and benefits of MI Paste/MI Paste Plus. It is acceptable to utilize MI Paste/MI Paste Plus immediately afterwards a high fluoride toothpaste/oral rinse as the RECALDENT™ (CPP-ACP) helps to retain the fluoride on the tooth surface promoting the incorporation of the fluoride ion into the tooth surface creating a stronger fluorapatite tooth surface. Why add fluoride to MI Paste? MI Paste Plus is a superior form of fluoride ions as it also contains CPP-ACP. MI Paste Plus therefore contains bioavailable calcium ions, phosphate ions and fluoride ions*. MI Paste Plus enhances mineral release without encouraging the formation of calculus. MI Paste Plus is prophylactic and easy to use both in function and at home, and tin can even exist claimed on a patient's insurance as fluoride treatment. It likewise does not irritate dry mouths caused by certain medications. - Utilize MI Paste Plus:
- For patients who experience tooth sensitivity
- For sensitivity earlier and after tooth whitening
- For desensitizing
- Does not irritate dry out mouths caused by certain medications
REFERENCES:
* Reynolds 1998, Reynolds et al 2006
- Reynolds EC. Spec. Care Dentist eighteen: 8-xvi, 1998
- Reynolds EC. J Dent Res (in press), 2006
- Ten Cate JM. Acta Odontol Scand 57:325-329, 1999 How does fluoride and CPP-ACP work? Four Fluoride ions promote the formation of fluorapatite in the presence of calcium ions and phosphate ions. This is now believed to be the major mechanism of fluoride ion's action in preventing molar decay. Nevertheless, fluoride ions tin but promote strengthening of the tooth enamel with fluorapatite if plenty salivary or plaque calcium and phosphate ions are bachelor when the fluoride is topically applied. Hence, on topical application of fluoride ions, the availability of calcium ions and phosphate ions are the limiting factor for net enamel strengthening to occur (Ten Cate, 1999). MI Paste Plus is a superior form of fluoride ions as it as well contains CPP-ACP. MI Paste Plus therefore contains bio-available calcium ions, phosphate ions and fluoride ions. CPP-ACP plus fluoride has been shown to increase fluoride'south uptake into plaque and subsurface enamel and substantially increase subsurface enamel strength in situations with fluorapatite relative to fluoride alone, past providing bio-bachelor calcium ions, phosphate ions and fluoride ions in the correct molar ratio to form fluorapatite. How much fluoride is in MI Paste Plus? MI Paste Plus contains 900 parts per million (ppm) fluoride ions a level but beneath that found in normal adult-strength toothpastes (1000 ppm). While the strengthening actions of the fluoride ions are well known, MI Paste Plus with ACPF releases fluoride as well as calcium and phosphate ions, thereby providing all the three ions which are required for formation of acid-resistant fluorapatite. This level of fluoride likewise exerts some furnishings on the utilization of sugars as an free energy source by dental plaque leaner, which reduces their overall contribution to plaque fermentation. How is fructose metabolized? It is desirable to minimize patients' high frequency consumption of fermentable dietary substrates, including those in foods, drinks, and medications. Nonfermentabel dietary sweeteners are recommended whenever possible, such as xylitol, sorbitol, aspartame or saccharin. The polyols such every bit xylitol are anticariogenic equally they result in decrease acid fermentation past S. Mutans. Fructose is a monosaccharide, or unmarried sugar, that has the same chemical formula as glucose but a different molecular structure. Sometimes chosen fruit sugar, fructose is found in fruit, some vegetables, honey, and other plants. Fructose and other sugars are carbohydrates, an important source of free energy for the body. Does MI Paste/MI Paste Plus take FDA 510K Clearance? MI Paste received FDA 510K Clearance to sell and market place MI Paste on Oct 20, 2004 (KO42200). MI Paste Plus received FDA 510K Clearance on April 12, 2007 (KO70854). Both MI Paste and MI Paste Plus have FDA 510K Clearance equally a prophy paste and for treating hypersensitivity. MI Paste and MI Paste Plus are cleared in Canada by Health Canada. Recommended Indications:
To exist used for cleaning and polishing procedures as function of a professionally administered prophylaxis treatment. Secondarily, MI Paste/MI Paste Plus tin be used for the management of tooth sensitivity, mail service scaling, root planing and bleaching. Please Annotation: The FDA does not give approvals but clearance based on the data submitted. 510K Clearance:
MI Paste - K042200
MI Paste Plus - K070854 Is MI Paste/MI Paste Plus canonical by the FDA? Yes, GC America received clearance to sell and market MI Paste on: Oct. 20, 2004, K042200. MI Paste Plus received clearance to sell and market on: April 12, 2004, K070854. MI Paste and MI Paste Plus are cleared in Canada by Health Canada. A patient is allergic to strawberries, can they use MI Paste strawberry season? I know the flavor comes from artificial flavoring, but I am not certain if real fruit is used at any point. MI Paste's flavoring agent is artificial. No real fruit is used in the flavoring process. Is fluoride necessary for enamel to uptake calcium and phosphate ions? Fluoride is benign merely non necessary for the calcium and phosphate ion to be beneficial to the tooth substrate. Is it okay to rinse with fluoride prior to using MI Paste instead of fluoride toothpaste? Brushing with 900/1000 ppm toothpaste is adequate and and so utilize MI Paste. If using a high strength toothpaste (5000 ppm or more) it is suggested to wait at least 2 hours before applying MI Paste. The same goes for rinsing with a high fluoride rinse. Is toothpaste or fluoride rinse to be rinsed after apply or simply spit out to maximize the corporeality of fluoride bachelor? Brush your teeth with your regular toothpaste 900 ppm, including spitting and rinse the mouth, then apply MI Paste. What type of fluoride is better to combine with MI Paste, stannous or sodium fluoride? 1 fluoride is not meliorate than the other. Stannous fluoride has a trend to stain, which is why sodium fluoride is more popular. Exercise not combine, carve up applications specially if using a high fluoride product like Prevident. A suggestion, have the patient utilize the high fluoride in the AM and MI Paste in the PM. Again with the high dose you desire to separate treatment, you may desire to expect 2 - 3 hours. Should MI Paste be used later every fluoride treatment? Yes, studies at the University of Melbourne have demonstrated that RECALDENT™ (CPP-ACP) significantly increased the uptake of fluoride into the tooth enamel creating fluorapatite that is more resistant to acid challenge. Thus MI Paste is recommended for treatment of patients of both loftier and depression caries risk. In terms of a patient who has a low caries risk, a six monthly awarding of neutral sodium fluoride gel followed by MI Paste is recommended. In patients who use no fluoride products, RECALDENT™ (CPP-ACP) will still be effective, since in all patients there are halo effects of fluoride in the water and in their diet. CPP-ACP is able to strengthen tooth structure in the complete absence of fluoride, and this is through the formation of hydroxyapatite. Is MI Paste an alternative to fluoride for anti-fluoride patients? Yes, the fact that MI Paste is derived from the milk protein, casein, information technology is completely natural and safe and therefore is often an effective preventive treatment for patients who are anti-fluoride. -
Grinding, Sensitivity and MI Paste Please talk with your dental professional about grinding and what can be done to assist alleviate the discomfort. MI Paste can be used for patients with ambitious tooth wear, where the molar surfaces have go sensitive. Delight keep in mind, MI Paste volition non supervene upon the enamel y'all wore down. MI Paste volition assistance to reduce sensitivity. Does MI Paste or MI Paste Plus contain Gluten? Nosotros ostend that MI Paste/MI Paste Plus does not contain gluten. It contains nothing other than the ingredients listed on the tube and box. Why is propylene glycol in MI Paste/MI Paste Plus? Propylene glycol is used in oral pastes as a thickening agent. It is digestible and the body turns it into lactic acid. Propylene glycol is safe and is listed by the FDA every bit GRAS ("More often than not Regarded As Prophylactic"). Diethylene glycol is toxic. -
With so many other options available for dentinal hypersensitivity, why MI Paste? When MI Paste with RECALDENT™ (CPP-ACP) is practical onto the surface of dentin, the protein component bonds strongly and subsequently mineral plugs form, which begin to block the tubules. Several clinical studies have shown that MI Paste has a potent long acting desensitizing effect when used in patients with cervical sensitive dentin. MI Paste with RECALDENT™ (CPP-ACP) applied at to the lowest degree once daily provides both immediate and long term solutions to the common problem of dentinal hypersensitivity. It tin can arrest the procedure of dental erosion, which is a mutual underlying crusade of chronic tooth sensitivity. What is a hydroxybenzoate allergy?
What sort of products contain hydroxybenzoate?
How would someone know if they are allergic to hydroxybenzoate?
Is hydroxybenzoate in nutrient, sunscreen?
Is hydroxybenzoate a preservative? Para-hydroxybenzoate is often called as Paraben and is widely used as preservatives in the cosmetic and pharmaceutical industries, such as shampoos, lotions, toothpaste etc. They are besides used as food additives. Parabens are considered to be safety, but can cause skin irritation or dermatitis on some individuals with Paraben Allergies. Should a patient consider incorporating MI Paste into their daily dental homecare? The MI Paste protocols are intended for moderate to high chance patients. All the same, keep in mind that loss of strength within the teeth and restrengthening occurs continuously in the mouth. In one case you have reversed the negative effects of the losing strength within the teeth, yous will need to maintain a healthy oral cavity. If a patient has experienced the loss of strength within the teeth in the by, the patient tin can merely benefit from incorporating MI Paste into their daily dental routine. Just as we have continuous exposure to fluoride we need the continuous exposure of calcium and phosphate in MI Paste. -
What are the ingredients in MI Paste? All the ingredients in MI Paste, MI Paste Plus and GC Dry out Mouth Gel are listed on the box and tube. MI Paste: pure water, glycerol, CPP-ACP, D-sorbitol, CMC-Na, propylene glycol, silicon dioxide, titanium dioxide, xylitol, phosphoric acrid, flavoring, zinc oxide, sodium saccharin, ethyl p-hydroxybenzoate, magnesium oxide, guar gum, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate (available in mint, vanilla, strawberry, melon, tutti-frutti). MI Paste Plus: pure water, glycerol, CPP-ACP, d-sorbitol, CMC-Na, propylene glycol, silicon dioxide, titanium dioxide, xylitol, phosphoric acid, sodium fluoride, flavoring, sodium saccharin, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate (available in mint, vanilla, strawberry, melon, tutti-frutti). Why does the IFU specify Vanilla for Xerostomia? Vanilla has the well-nigh neutral sense of taste which we found with field evaluations. MI Paste does not irritate dry mouths. -
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Is MI Paste/MI Paste Plus Kosher? Yes, MI Paste and MI Paste Plus are Kosher. Please contact the MI Paste/MI Paste Plus Customer Service Department for more information. Can a patient on kidney dialysis utilize MI Paste? Dialysis patients must seek approval from their doctor before using MI Paste/MI Paste Plus, although the amount of ingestion of phosphate by using MI Paste would be very pocket-size. Consultation between physician and dental professional may lead to a modification of the therapeutic application. The amount of phosphate contained in a MI Paste 40g tube is more than 0.two%. We say "more than" considering 0.2% is phosphoric acid past itself and CPP-ACP too contains phosphate. The recommended therapeutic dose is ane gm. per awarding. Though this product tin exist ingested afterward therapeutic application it is not how the product is used to deliver a therapeutic dose. Note, We do not testify a warning well-nigh phosphate for dialysis patients in the instructions. Instead, we bear witness all the ingredients on the tubes and boxes. -
Does MI Paste contain lactose? MI Paste/MI Paste Plus contains RECALDENT™ (CPP-ACP), information technology is milk derived with lactose content less than 0.01%. The amount is very small. -
Does MI Paste/MI Paste Plus accept melamine, do they use milk from China to create MI Paste? The milk used to create RECALDENT™ (CPP-ACP) comes from the dairy cows of New Zealand. The milk does non originate from Red china. We capeesh your concern for safety and assure you that MI Paste/MI Paste Plus does not contain melamine. When To Use MI Paste Plus Rather Than MI Paste? MI Paste is the just product for professional person use containing RECALDENT™ (CPP-ACP), a special milk-derived poly peptide that releases calcium and phosphate to the surface of the teeth. MI Paste and MI Paste Plus are water-based and sugar-costless topical molar crèmes. - MI Paste:
- Relieves tooth sensitivity
- Does non irritate dry mouths caused past certain medications
- Helps minimize molar sensitivity before and after professional person cleaning
- Is helpful during orthodontics relative to helping command (or reduce) dentin sensitivity
- Is not a toothpaste; information technology is a topical molar crème that tin can be used safely several times daily
- Use MI Paste:
- For desensitizing
- For sensitivity earlier and afterward tooth whitening
- For children six years and under and pregnant women
MI Paste Plus offers the same benefits of MI Paste, simply is enhanced with a patented form of fluoride (900 ppm). MI Paste Plus enhances mineral release without encouraging the germination of calculus. MI Paste Plus is safe and easy to apply both in function and at home, and can even be claimed on a patient'south insurance as fluoride handling. It as well does non irritate dry mouths caused by sure medications. - Use MI Paste Plus:
- For patients who experience tooth sensitivity
- For sensitivity before and after tooth whitening
- For desensitizing
- Does not irritate dry mouths caused past certain medications
Is MI Paste/MI Paste Plus safe for patients with milk allergies? The agile ingredient in MI Paste/MI Paste Plus is RECALDENT™ (CPP-ACP). RECALDENT™ (CPP-ACP) is milk-derived and should not be used by patients with milk poly peptide allergies. Casein phosphopeptides are derived from milk casein (a milk protein). Do Not employ MI Paste/MI Paste Plus if you lot have a proven or suspected milk protein (IgE) allergy. What separates MI Paste from other calcium products? RECALDENT™ (CPP-ACP) technology has been extensively researched at the University of Melbourne Dental School (Australia) since the 1980'south. There are over 100 studies substantiating the benefits of RECALDENT™ (CPP-ACP), the agile ingredient in MI Paste. What is MI Paste Plus? MI Paste Plus has all the benefits of MI Paste, but contains a unique, patented form of fluoride (900 ppm). MI Paste Plus provides a superior form of fluoride ions as it besides contains CPP-ACP (casein phosphopeptide-amorphous calcium phosphate). CPP-ACP + fluoride (F) has been shown to increase fluoride's uptake into plaque and subsurface enamel and essentially increase subsurface enamel strengthening in situations with fluoroapatite relative to fluoride alone, past providing bio-bachelor calcium, phosphate and fluoride ions in the correct molar ratio to form fluoroapatite in the body of the lesion, not just at the surface layer. For children under half dozen years of age, the use of the regular MI Paste is recommended. - MI Paste Plus:
- For patients who experience tooth sensitivity
- For sensitivity before and after tooth whitening
- For desensitizing
- Does not irritate dry mouths caused past certain medications
Why MI Paste Plus with fluoride vs Prevident booster? MI Paste with RECALDENT™ (CPP-ACP) combined with a low dose fluoride applied regularly aids for thorough tooth-strengthening extending to the depth of the enamel rod, versus superficial strengthening which may extend partially in depth. -
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Is ane application of MI Paste beneficial? Yes, peculiarly after and/or with a professional fluoride application because MI Paste with RECALDENT™ (CPP-ACP) promotes the uptake of fluoride ion past tooth enamel. MI Paste may also be used for a patient who has a sensitivity trouble. MI Paste could be used as a unmarried application for a patient who had cervical dentinal hypersensitivity where nigh of the issues of lifestyle were comfortably addressed at that same visit. If 1 had concerns about compliance, then the patient could be given MI Paste to take abode with them. -
Does MI Paste/MI Paste Plus incorporate whey protein? At that place are ii varieties of proteins that exist in milk. The most prominent is casein, which represents 80% of the protein in milk, and the other, which is much more widely recognized, is whey. Whey is eliminated during the manufacturing of casein, and then should not exist included in MI Paste. GC has not tested the presence of whey in the terminal product of MI Paste. Delight consult your medico or dentist prior to using MI Paste or MI Paste Plus with any concerns earlier using. Can patients with phenylketonuria (PKU) use MI Paste or MI Paste Plus? MI Paste/MI Paste Plus are non phenylalanine-free products. A tube of twoscore grams of MI Paste/MI Paste Plus contains less phenylalanine than 100 mL of milk. We recommend that the patient should consult a doctor before using the product to check if the amount is inside the adequate level. Is MI Paste/MI Paste Plus condom to use for my cat or dog? MI Paste and MI Paste Plus have never been tested on cats or dogs. Nosotros recommend you check with your veterinarian. All the ingredients are listed on the box/tube for your veterinarian to make a professional person decision. Milk is listed as an ingredient that should not be given to pets co-ordinate to the American Lodge for the Prevention of Cruelty to Animals (ASPCA). Take your box and tube of MI Paste/MI Paste Plus to your veterinarian and show him/her the ingredients that are listed; your professional veterinarian knows what is acceptable for your favorite pet'due south wellness. Please note: MI Paste does not contain fluoride; MI Paste Plus does incorporate fluoride. Does MI Paste/MI Paste Plus contain peanuts?
Is it manufactured on machinery that may contain peanuts? MI Paste and MI Paste Plus do not contain peanuts. MI Paste and MI Paste Plus are not manufactured on any machinery that contains peanuts. Does MI Paste contain parabens? - Yes, as stated on the SDS for MI Paste Plus:
- Ethyl-4-hydroxybenzoate 120-47-8 N.East. North.East <0.1
- Butyl-parahydroxybenzoate 94-26-viii Due north.Due east. Northward.E <0.ane
- Propyl-4-hydroxybenzoate 94-xiii-3 North.E. Northward.E. <0.1
Based on the chemical compounds, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate and butyl p-hydroxybenzoate are esters of the paraben family unit. Parabens are a class of chemicals widely used as preservatives in the cosmetic and pharmaceutical industries. Parabens are constructive preservatives in many types of formulas. Parabens methyl, ethyl, and propyl esters of p -hydroxybenzoic acid used together. Parabens are esters of para-hydroxybenzoic acid, from which the proper name is derived. Common parabens include methylparaben, ethylparaben, propylparaben and butylparaben. Less common parabens include isobutylparaben, isopropylparaben, benzylparaben and their sodium salts. Why is there no patient instruction in the box? How to utilize MI Paste/MI Paste Plus is dependent upon why and how the dental professional recommends information technology application. Information technology is a case by case situation. Ask your dental professional for clarification on frequency and method/of awarding. What About Pregnant Mothers?
Is MI Paste safe to use while pregnant? There are no proven dental or general health benefits or risks from pre-natal fluoride containing products. Fluoride supplements are not indicated in pregnancy. Regular use of MI Paste during pregnancy helps to maintain elevated levels of calcium and phosphate in the saliva, In that location is also an additional benefit because MI Paste volition inhibit the growth and adhesion of mutans streptococci, which would otherwise flourish in an acidic oral environment. Any MI Paste fabric that is swallowed is completely condom, and volition contribute towards dietary calcium. However, it is always best to check with your dental professional or doctor before using. What is the pH of MI Paste? The pH of MI Paste is 7.viii. it is considered a neutral pH based on a range of 0 – 14 scale. 11/13/2008 What is pH? pH is the measurement of the hydrogen ion concentration, [H+]. This value ranges from 0 to xiv pH. Values below 7 pH exhibit acidic properties. Values higher up seven pH exhibit basic (likewise known every bit caustic or alkaline) properties. Since 7 pH is the center of the measurement scale, it is neither acidic nor basic and is, therefore, chosen "neutral." Ane fashion to mensurate pH is by indicators, materials that are specifically designed to change color when exposed to different pH values. The color of a wetted sample paper is matched to a colour on a color chart to infer a pH value. pH paper is available for narrow pH ranges (for example, 3.0 to 5.5 pH, iv.5 to vii.five pH and 6.0 to eight.0 pH), and fairly wide pH ranges of 1.0 to 11.0 pH. What purpose is the phosphoric acid serving?
How much is in there and volition it have whatsoever consequence in demineralizing enamel? The purpose of the phosphoric acrid is to buffer the CPP-ACP. MI Paste is an exceptionally expert buffer of acrid notwithstanding we nevertheless need the formulation to be relatively neutral to be able to get the most effective levels of molar-strengthening. The final pH of MI Paste is around vii.viii (slightly element of group i), without the phosphoric acid it would be higher (more alkaline) which is helpful for buffering an acidic rima oris simply not as effective for the strengthening process. Phosphoric acid is used to adjust the pH of MI Paste to get it close to neutral instead of alkaline (basic). The per centum composition of phosphoric acrid is < 00.3% (ie less than .3 of 1 percent) so it is very small-scale. You can imagine it is more than added equally a formulation "tweak" to ensure the optimum performance balancing between buffering and strengthening benefits. In that location is admittedly goose egg chance/potential for losing strength inside the teeth. Is MI Paste available past prescription or is just distributed through dental offices? MI Paste is at present available either from your dental professional or by prescription from your dental professional person. The patient would go to the online pharmacy world wide web.mountainside-medical.com to buy MI Paste. At present you take ii options to obtain MI Paste, either from your dental professional person or from www.mountainside-medical.com. Please note, it is not bachelor from your local pharmacy it is only bachelor from the online chemist's www.mountainside-medical.com. MI Paste is only available from either your local dental professional person or through www.mountainside-medical.com with a prescription from your dental professional. - Patient receives prescription for MI Paste from their doctor/dentist
- Patient goes to www.mountainside-medical.com to place society
- Questions: call 1-866-885-0508 or email sales@mountainside-medical.com
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Radiation Treatment for Cancer Patients
Can a patient with pharynx cancer use MI Paste/MI Paste Plus during radiations treatment?
Can a patient use MI Paste during the radiation treatment even with the presence of titanium dioxide and zinc oxide listed in the ingredients?
Will the presence of titanium and zinc oxide cause "radiation scatter" to areas not intended for radiations? MI Paste/MI Paste Plus tin be used during Radiation treatment cycle. However, it is suggested to refrain from applying MI Paste/MI Paste Plus for 24 hours prior to radiation therapy to minimize whatsoever potential "scatter radiations" issues. This is due to the presence of titanium dioxide and zinc oxide in MI Paste. Similar to when radiologists recommend no deodorant prior to mammography'south to minimize "scatter radiation." Equally ever, it is best to talk with your radiation/oncologist prior to your radiation treatment about applying MI Paste during your radiation treatment. -
Would MI Paste exist beneficial to patients with Sjogren'due south Syndrome? The combination of a reduced salivary menstruum and ocular dryness may indicate Sjogren's Syndrome. A patient with Sjogren's Syndrome would do good from MI Paste Plus. The suggested home care plan would include MI Paste twice daily. Others aids include a saliva substitute, for comfort, (GC Dry out Rima oris Gel past GC America) and intermittent chlorhexidine therapy and/or fluoride treatment to suppress harmful bacterial. Always bank check with your dental professional person. Are there any Salicylates in MI Paste?
Are there whatever natural or artificial salicylates in any of the flavorings, CPP-ACP, CMC-Na and Xylitol? Salicylates are a naturally occurring group of chemicals found in a wide range of foods, herbs and spices. Salicylates are similar in structure to salicylic acid which is manufactured to produce aspirin. Some people may exist sensitive or allergic to aspirin and also react to foods containing salicylates. Fruit containing salicylates include: Apricot, avocado, blackberry, black currant, blueberry, boysenberry, cherry, cranberry, currant (stale), engagement, grape, grapefruit, guava, Jonathan apple, kiwi fruit, lychee, standard mandarin, mulberry, nectarine, orange, passionfruit, peach, pineapple, plum, prune, raisin (dried), raspberry, reddish currant, rockmelon, strawberry, sultana (dried), watermelon etc. Nutrient intolerance is a general term used to describe an adverse reaction to certain types of foods. Intolerance to salicylates is a relatively common condition which can exist managed by avoiding foods which contain these substances. The main food sources of salicylates are fruits, vegetables, dried spices, tea and food flavorings. The average 'Western nutrition' has an estimated salicylate intake ranging from 10 to 200 mg per day. - MI Paste is GRAS ("Generally Regarded as Safe")
- Salicylate is not added and not listed
- Flavor is the concern although salicylate is not listed on the flavors we are using, reviews on the public domains ( http://www.webmd.com/allergies/guide/salicylate-allergy ) indicate that salicylate is found in many flavors (unfortunately, season receipts are manufactures merchandise clandestine, and GC does not accept the compound profile of the flavors)
- As nosotros do not have a specific QA assay for salicylates in MI Paste, we are non in a position to state the product is salicylate-free, or its level is safe to a specific patient
Sensitivity during the prophylaxis and the benefits of applying MI Paste Today I had one of my super sensitive Perio patients in that I numb with topical and paw scale only. Instead today I polished first with MI Paste. I usually have the patient rinse but since this patient was hypersensitive, I kept the paste on and scaled. When I got to the deeper pockets I put some paste on the tip of the scaler to assist desensitize subgingivally (just similar I do with the topical.) For the kickoff time always the patient said she had NO DISCOMFORT during the cleaning!!!! I'grand so excited, yet another manner to use that crawly MI Paste Plus. It works like a charm.
-Michelle in VA -
What time of day is best to use MI Paste? In terms of the bounden properties of MI Paste, CPP-ACP binds to oral soft tissues, to dental pellicle and besides to plaque. This binding elevates the salivary levels of calcium and phosphate for extended periods. For this reason, MI Paste works best in patients when it is applied at night before bed, since the salivary clearance rate is low during sleep. In patients who need intensive treatment, and so a twice daily application is sufficient in most individuals. It is recommended that MI Paste exist practical immediately after flossing and brushing with a yard ppm fluoride toothpaste, particularly at night earlier bed. RECALDENT™ (CPP-ACP), the active ingredient of MI Paste, is extremely effective for desensitizing. Some patients who have generalized cervical dentinal hypersensitivity, thus one needs to look carefully at their lifestyle (using particularly the resting salivary parameters) to gain insight into whether they accept sub-clinical dehydration. Some patients who have generalized cervical dentinal hypersensitivity, may also have dental erosion, and thus one needs to look advisedly at their lifestyle (using particularly the resting salivary parameters) to proceeds insight into whether they have sub-clinical dehydration. Why would I cull to employ custom trays to administer MI Paste, when I can employ MI Paste with a clean finger and let the MI Paste sit for iii-five minutes? You can utilise MI Paste with either a custom tray or with a clean finger. One method is not better than some other. Bank check with your dental professional to make up one's mind what method of delivery would work all-time for you. What is the purpose of adding Titanium Dioxide to MI Paste? Titanium Dioxide is used to give the white opaque wait to MI Paste. Titanium Dioxide is found in various corrective and dental products as well every bit MI Paste. It is widely used as a food condiment and as a pigment in icings for baked appurtenances, in tobacco wrappings and tobacco substitutes, in saccharide syrup coatings for products sold in tablet form, and to whiten and aged cheese. In health products, Titanium Dioxide is used in sunscreens, as a dusting pulverization, and in ointments and lotions. Titanium Dioxide is likewise used as a paint in paints, varnishes, enamels, and lacquers to impart whiteness, opacity, and brightness; and in paper coatings and fillers to improve opacity and brightness. -
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Why does the IFU specify Vanilla for Xerostomia? Vanilla has the most neutral taste which we plant with field evaluations. MI Paste does not irritate dry mouths. I have a patient who is a vegan, is the calcium and phosphate in MI Paste/MI Paste Plus derived from an animal source? The agile ingredient in MI Paste/MI Paste Plus, RECALDENT™ (CPP-ACP) is derived from the milk poly peptide from cows. MI Paste/MI Paste Plus is non considered a vegan product. Does MI Paste Plus comprise any ingredients that could exist harmful to porcelain veneers or their bond to tooth structure? MI Paste Plus does not contain any ingredients that volition have a negative effect on porcelain veneers or bonding. We have not received whatsoever complaints that porcelain does not bail to tooth surfaces for patients who uses MI Paste Plus. Of course, it should not be used in the middle of bonding procedure. How does MI Paste Plus compare to Fluoride rinse or varnish? Fluoride rinses contain between 200 and 900 ppm fluoride, while varnishes contain betwixt 22,600 and 25,000 ppm fluoride. These can be effective preventive agents in patients with enhanced risk, simply normal salivary function. MI Paste Plus has 900 ppm of fluoride. MI Varnish™ has 22,600 ppm of fluoride, and is for moderate to high caries hazard. Also MI Varnish™ could be beneficial in cases where compliance is an issue. -
Does MI Paste/MI Paste Plus contain whey protein? At that place are two varieties of proteins that be in milk. The near prominent is casein, which represents fourscore% of the protein in milk, and the other, which is much more widely recognized, is whey. Whey is eliminated during the manufacturing of casein, and then should non be included in MI Paste. GC has not tested the presence of whey in the concluding product of MI Paste. Please consult your dr. or dentist prior to using MI Paste or MI Paste Plus with any concerns before using. What does w/w mean on the MI Paste Plus packaging? Due west/Westward is an abbreviation for "by weight," used in chemistry and pharmacology to depict the concentration of a substance in a mixture or solution. Properly speaking, ii% westward/w means that the mass of the substance is 2% of the total mass of the solution or mixture. The metric symbol thou/thou has the same meaning as w/w. W/Due west stands for weight per weight. When we prepared a tube for Molar Mousse Plus prior to the launch in Australia, we checked the labelling of fluoride contained toothpaste available from Colgate. They stated like "Active ingredients: Sodium Fluoride 0.22% W/Westward". We likewise checked the OTC drug labelling guideline by FDA and found that they recommended to put both of per centum and ppm on the package, equally ppm might be confusing for the stop-users. Therefore we finally decided to put the amount both in ppm and percentage. -
What is the amount of xylitol in MI Paste?
How much MI Paste would it take to accomplish the therapeutic level for xylitol? MI Paste and MI Paste Plus both contain two% Xylitol. Studies accept shown that a therapeutic dose to reduce dental caries is 6-10 grams per mean solar day, distributed over iii-5 time periods. Most pieces of xylitol glue have about ane.v grams each. Many products incorporate less than therapeutic amounts of xylitol, often in combination with other sweeteners. Information technology is desirable to minimize patients' high frequency consumption of fermentable dietary substrates, including those in foods, drinks, and medications. Nonfermentable dietary sweeteners are recommended wherever possible, such as xylitol, sorbitol, aspartame, or saccharin. The polyols such as xylitol are anticariogenic, as they result in decreased acrid fermentation past Due south. Mutans. Why does the IFU specify Vanilla for Xerostomia? Vanilla has the most neutral sense of taste which we institute with field evaluations. MI Paste does non irritate dry mouths. -
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